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GSSG generated in these processes can be either recycled to GSH by a NADPH-dependent reaction, catalyzed by GR 3 , or pumped out of the cell by ATP-dependent processes, with multidrug resistance-associated protein-1 (MRP-1) being the major pathway for GSSG efflux 33

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17,173,184,190 The prognosis for DRPN is generally favorable, with many patients experiencing significant recovery over months to years, although some may have residual weakness, particularly with early diagnosis and appropriate management

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Psychoneuroendocrinology, 2014