Expected eligibility mirrors current GLP-1 approvals: BMI 30, or BMI 27 with a weight-related condition
Similar effects were observed also after Topiramate supplementation, an antiepileptic drug used also in the treatment of atypical psychoses that acts as modulator on Na + channels, gamma-aminobutyric acid (GABA) concentrations, and -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) and kainate receptors
But an essential function related to weight loss is the sensation of hunger and fullness controlled by the hypothalamus.[1]
The relationship between specific GC and neurocognitive outcomes is possibly influenced by age at diagnosis and sex, with older age at diagnosis and use of dexamethasone being associated with worse IQ, processing speed, spelling, and reading while younger age at diagnosis with prednisone is associated with worse functioning [90]
If you experience any persistent or concerning symptoms, contact your GP or diabetes specialist nurse for guidance
