Tumor spheroid viability assay K1 cells were incubated to form spheroids (~ 7 days) in ultra-low binding 96-well plates for viability assay and in ultra-low binding 24-well plate for imaging with PI staining
The company submitted tirzepatide under the brand name Mounjaro with a list price of approximately $1,069 per month before insurance, making access a barrier for many eligible patients
Clinical trials show that approximately 9.8% of patients discontinue Saxenda treatment due to gastrointestinal adverse events
Common antacids include Tums, Rolaids, and Maalox
Recently, new therapies like Keytruda have radically changed the treatment of cancer, while more established therapies, like GLP-1s and SGLT2 inhibitors, have suddenly changed the treatment of diabetes and heart failure, respectively