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You must code: Whether the patient has a crisis The exact type of Crisis Any associated conditions For example: D57.01 Sickle-cell disease with acute chest syndrome D57.03 With splenic sequestration D57.00 Without Crisis If the patient is NOT in Crisis, say it clearly in the note

Biomedicines , 10 (11), 2696

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Physiological activation during normal healing operates differently than sustained pathological activation in cancer