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Berberine analogue IMB-Y53 improves glucose-lowering efficacy by averting cellular efflux especially P-glycoprotein efflux

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If metformin becomes difficult to tolerate due to semaglutide-induced nausea, your doctor may temporarily reduce the metformin dose or switch to a modified-release formulation that is gentler on the stomach

Body weight was assessed daily just before the start of the dark cycle