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As noted above, the mid-region residues (S19 Cagri- P25 Cagri ) form the prototypical bypass motif that was observed for rAmy/San385, constrained by conserved intramolecular hydrogen bonds between the backbone of L16 Cagri /F23 Cagri and S20 Cagri , and the backbone of P25 Cagri and N21 Cagri (Fig

Moreover, in both young and aged diabetic mice subjected to MCAO, exendin-4 treatment was shown to significantly polarize microglia/macrophages towards an anti-inflammatory M2 phenotype in the injured hemisphere compared to the non-injured hemisphere [76]

Xie, Y., Choi, T., & Al-Aly, Z

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