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After cell lysis, cDNA synthesis was carried out (Maxima Reverse Transcriptase, Thermo Fisher), followed by PCR (2 Kapa Hotstart Ready mix, VWR, 15 cycles)
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Semaglutide lowers blood sugar in a few ways: It increases insulin release
On the other hand, increasing glucose oxidation reduces lactate and H+ ion accumulation, thereby preventing intracellular acidosis in myocardial cells during ischemia, which aids in the faster recovery of ischemic heart function during reperfusion
It has strong antioxidant and neuroprotective effects in the brain, reducing oxidative stress which is thought to sometimes play a role in ADHD pathology
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