Supply Shortages In late 2024 and early 2025, the UK had significant shortages of GLP-1 medicines, especially: Wegovy, because demand is very high Ozempic, which caused problems for some diabetes patients If you are considering starting treatment, discuss the available options with your doctor
Both are safe when used correctly
Starting with a lower dose and gradually increasing (dose titration) helps minimise these symptoms
Thankfully, there are also many natural beta blockers that boast similar effects
These drugs mimic the physiological effects of GLP-1 by binding to GLP-1R, which enhances insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces food intake (Drucker, 2018)