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Appetite Suppression GLP-1 receptor agonists like semaglutide may help reduce appetite, leading to decreased food intake and subsequent weight loss

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Perhaps not surprisingly, the combination led to severe constipation that was punctuated by medication-provoked diarrhea episodes

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Liver fat reduction: a bonus benefit An important secondary finding from the clinical trials: after 48 weeks of treatment with the two highest doses of retatrutide, 90% of participants with elevated liver fat at baseline achieved normalization