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Norrving 3 , Per Wester 4,5 , Signild sberg 1 1 Department of Medical Sciences, Uppsala University, Uppsala, Sweden, 2 Uppsala Clinical Research Centre (UCR), Uppsala University, Uppsala, Sweden, 3 Department of Clinical Sciences, Lund University, Lund, Sweden, 4 Department of Public Health and Clinical Science, Ume University, Ume, Sweden, 5 Department of Clinical Science, Karolinska Institute, Stockholm, Sweden Background and Aims: The Timing of Oral Anticoagulant Therapy in Acute Ischemic Stroke with Atrial Fibrillation (TIMING) study and other recent randomised trials demonstrate benefit of early initiation of direct oral anticoagulants (DOACs) on composite outcomes