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The animal study was approved by Institutional Animal Care and Use Committee - University of Southern California

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Selenium is a trace element which is located in selenoenzymes, comprising thioredoxin reductase (TrxR) that is an enzyme which is related to the reduction of proteins and disulfides and glutathione peroxidase (GPx) for the detoxification of H 2 O 2 [93, 94, 95]

Several studies have not gone further to dissect the human microbiota in terms of composing the genetic material of the microbes, proteins, and metabolic pathways that maybe essential in understanding the etiopathogenetic position of the microbiota (Figure 2 showed the Strategies to modify gut microbiota for disease treatment include probiotic-rich dairy, fruits, and beverages, along with powders and microencapsulated forms to enhance digestive and mental health