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PMID: 40729432 Cancer Cell Int2022 Oct 7;22(1):304

However, when RBCs are saturated with carbon monoxide, Prx2 was observed only in the active form in the cytosol and none in the oxidized form, suggesting that Prx2 is acting specifically to protect Hb, shifting its function from peroxidase to chaperone

Nevertheless, observational studies such as these cannot determine whether low levels of vitamin B12 were the cause of the weight gain or whether higher levels of vitamin B12 protected against lower levels