Evidence-based approaches include: Cognitive behavioural therapy (CBT) and stress management techniques Regular physical activity and adequate sleep hygiene Mindfulness-based stress reduction programmes Addressing underlying anxiety or depression with appropriate psychological or pharmacological interventions Patients with adrenal insufficiency require lifelong glucocorticoid replacement therapy, typically with hydrocortisone (1525mg daily in divided doses) to mimic physiological cortisol secretion patterns
This article is originally published at Insider Monkey .
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In a RCT comparing the effects of 60 mg/day of duloxetine and 1500 mg/day of ALC (t.i.d.) on pain, depression, anxiety and well-being in 65 female FMS patients, Leombruni and coll