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Over the past decade, peroxisome proliferator-activated receptor- coactivator-1 (PGC-1) has been demonstrated as a key transcriptional co-activator, providing a mechanistic insight into nuclear regulatory pathways in the biogenesis of mitochondria in skeletal muscle [7-9]

Low NAD+ levels are associated with ageing and being more prone to chronic diseases such as diabetes, heart disease, Alzheimers disease and vision loss