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While these changes are not well characterized in the literature, they represent hypothetical contributing factors to the subjective taste alterations patients report

Studies have indicated that HT thyroid tissues exhibit reduced GPX4 expression, leading to an imbalance in lipid peroxidation and antioxidant defenses, making thyroid cells highly susceptible to ferroptotic death (180, 181)

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Unlike GIP, the fully processed GLP-1 is produced by the neurons within the nucleus of the solitary tract (NST) in the brainstem of rats (139)

In the 52-week SURPASS-4 trial TZP was tested versus insulin glargine in diabetic adults and a high CV risk below not sufficient GC at baseline and in therapy with one to three oral glucose-lowering drugs (metformin, sulfonylurea, SGLT2-i)