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NNMT is expressed most highly in human liver (RPKM 188.3), followed by the appendix (RPKM 69.3) and approximately ten other tissues, with a biased expression pattern

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Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and constipation, which typically diminish with continued use and gradual dose escalation

If your belly fat started showing up around the same time as your hot flashes, thats a strong sign its linked to a hormonal imbalance