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Symptoms can include yellow discoloration of the skin and whites of the eyes, poor appetite, vomiting, tiredness, abdominal pain, or diarrhea

Glutathione peroxidase familyAn evolutionary overview

[DOI] [PMC free article] [PubMed] [Google Scholar] Buvelot H

Among the former, fluorescein staining of the ocular surface was scored according to the recommendations of the National Eye Institute/Industry workshop on clinical trials for dry eyes (NEI-SS) ( Tear samples were collected at visits V1, V3, V4, and V6 using Schirmer strips, as previously described in the literature ( 2.6 Analysis of cytokines in tears and HCEpiC cell cultures To determine cytokine levels from recovered tears and supernatant from treated HCEpiC cells, the LEGENDplex Human Inflammation Panel 1 (13-plex) flow cytometry-based assay kit was used (BioLegend, San Diego, CA)

Flow cytometry with MitoTracker Green confirmed that AGC1-deficient NPs had comparable mitochondrial mass to control cells despite their smaller size (Fig