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As humans do not produce TMCA, we examined the levels of non-12-OH FXR-antagonistic BA species in humans, and found that the levels of non-12-OH FXR-antagonistic BAs (HDCA and UDCA-related species) were positively correlated with T3 levels in euthyroid human study participants (Fig

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Mar 1 2023;13(3)doi:10.3390/metabo13030370