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It is designated for research use and should only be considered under veterinary supervision

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In one prospective controlled trial, 100 patients at a single center in Italy who had experienced inadequate response to DMARD therapy were randomly assigned to open-label treatment with infliximab 5 mg/kg every 6 to 8 weeks, etanercept 25 mg twice-weekly or adalimumab 40 mg every other week

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Many mechanisms are involved in the changes of mitochondrial dynamics and aging