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The morphological alterations and mortality of NTS incubated with PZQ + NAC were generally identical with those induced by drug alone (Additional file 1: Table S1 and Figure S5)

Despite Dihexas structural derivation from Ang IV, mechanistic studies have established that the compound does not act through the classical AT 4 receptor (insulin-regulated aminopeptidase, IRAP)

Prolonged use in high doses may impact kidney health and internal balance

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