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When the rapid onset or threshold concentration of a concomitant orally administered medication is a critical determinant of effectiveness (such as with analgesics, antibiotics, and oral contraceptives), the medication should be administered at least 1 hour prior to SYMLIN injection or 2 hours after SYMLIN injection [see WARNINGS AND PRECAUTIONS and CLINICAL PHARMACOLOGY ]

The compound can be used by women, though effects specific to female physiology have not been specifically studied

J Pharmacol Exp Ther 256:11891194 Shigesawa T, Sato C, Marumo F (1992) Significance of plasma glutathione determination in patients with alcoholic and non-alcoholic liver disease

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