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There are still key mechanistic and practical challenges, and I think ultimately whether GLP-1 [receptor agonists] can meaningfully alter neurodegeneration or help you to prepare new people with MS remains an open question for the field. For more information: Afsaneh Shirani, MD, can be reached at [email protected].

Abstract Aims/hypothesis Our aim was to assess treatment discontinuation, reinitiation and switching between drugs within the same drug class for glucagon-like peptide-1 (GLP-1) receptor agonists and sodium-glucose cotransporter 2 (SGLT2) inhibitors in individuals with type 2 diabetes