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explored the significance of the combined effects of metformin and simvastatin in glioblastoma, demonstrating that these drugs exert additive antitumor effects through mechanisms related to senescence [12]

doi:10.1016/j.jneuroim.2008.09.014 Dong H, Zhang W, Zeng X, et al

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Room temperature means room temperature, around 20 to 25 degrees Celsius