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This increases ROS production and lipid accumulation through peroxidation, resulting in apoptosis and ferroptosis [246,247,248]

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Cerebrovascular reactivity is indicative of the cerebrovascular system's capacity for contraction and dilatation in response to stimuli, such as variations in cerebral perfusion pressure and arterial CO 2 partial pressure levels

Most of the lcFAODs result in a distinctive acylcarnitine profile depending on which of the lcFAO enzymes is deficient (Table 1)

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