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Activation of POMC neurons leads to the release of alpha-melanocyte-stimulating hormone (-MSH), which subsequently binds to the melanocortin 4 receptor in the paraventricular nucleus of the hypothalamus and triggers appetite-inhibiting signaling cascade

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Long-term taurine supplementation leads to enhanced hepatic steatosis, renal dysfunction and hyperglycemia in mice fed on a high-fat diet

Clinicians then look to the clinical studies for a protocol

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