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Berardelli I, Serafini G, Cortese N, et al

This approach has been described as a senolytic strategy selectively eliminating senescent cells while sparing non-senescent cells that do not depend on the FOXO4-p53 interaction for survival

However, a dose of 0.5 mg/kg Nano-Lut was found to be more effective in its antioxidant action than Nano-Bc, as shown by the results of the oxidative stress parameters

It accomplishes this through a complex cascade of biological pathways, including the promotion of angiogenesis (the formation of new blood vessels), modulation of nitric oxide, and interaction with growth factors

Metformin and cancer hallmarks: shedding new lights on therapeutic repurposing