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Hatfield DL, Gladyshev VN
This review integrates current evidence on how brain peptides contribute to AD pathophysiology, summarizes recent progress in peptide-based therapeutic strategies and delivery platforms, and critically examines the remaining barriers to clinical translation, including bloodbrain barrier penetration, metabolic stability, off-target effects, and the need for biomarker-guided patient stratification
Conversely, they have already been shown to promote production of the anti-inflammatory cytokine interleukin-10, which could exert a protective effect against noninfectious versions of the condition
Understanding the differences between semaglutide options and brand-name medications like Ozempic can help patients make informed decisions with their healthcare provider