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Safety outcomes were comparable between treatment groups in both studies

Hepatic impairment (OFV = 1.281), water volume 50 mL vs 120 mL (OFV = 3.328), age 65 years (OFV = 3.024), sex (OFV = 0.102) and renal impairment (OFV = 2.099) were excluded in the final model (in that order)

Inactive Ingredients: Sodium chloride, hydrochloric acid (for pH adjustment), and water for injection

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The same review notes that the Philippine Food and Drug Administration warns against IV glutathione for skin lightening due to risks of liver damage and the absence of clinical proof