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In contrast, the corticolimbic system (including the hippocampus, basal ganglia, and amygdala) governs the cognitive and emotional aspects of feeding behavior (118)

Karlsson et al., 2013

Exposure to excessive heat or freezing can degrade the active ingredient, reducing potency and potentially creating degradation products

This distinction is important, as it helps clarify where GLP-1 signaling may intersect with aging biology