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[DOI] [PubMed] [Google Scholar] 206.Mak JC

NSAIDs exert their effect by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins involved in pain and inflammation (Williams Benzon et al., 2018

Figure 5 Since oxidative stress plays an important role in the pathogenesis of viral-associated cardiovascular and lung diseases, antioxidant intervention would be a rational approach to use for treating lower respiratory tract infections (Komaravelli and Casola, 2014) and balancing oxidative damage by enhancing antioxidant defense (Banjac et al., 2008

Mitochondrial production of reactive oxygen species mediate dicumarol-induced cytotoxicity in cancer cells

Targeting these dynamics may attenuate the epithelial damage and profibrotic microenvironment characteristic of IPF