This article explores how GLP-1 medications work, their safety profile, NHS prescribing criteria, and alternative evidence-based strategies for managing perimenopausal weight gain
Direct growth hormone replacement has been explored as a longevity intervention, but it carries meaningful risks, including insulin resistance, fluid retention, carpal tunnel syndrome, and theoretical promotion of existing tumors, because GH and its primary mediator IGF-1 have potent pro-growth signaling that is indiscriminate about what it grows
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Social isolation in rats inhibits oxidative metabolism, decreases the content of mitochondrial K-Ras and activates mitochondrial hexokinase (in Eng)
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