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[42] Additional effects [edit] Semaglutide typically causes a benign increase in resting heart rate (around 3 beats per minute), which has not been associated with adverse cardiovascular events

In diabetes management, this medication enhances insulin secretion, inhibits glucagon release, slows gastric emptying, and decreases hepatic glucose production

Research shows that patients who view semaglutide as part of a comprehensive lifestyle change, rather than a quick fix, maintain their weight loss for years after starting treatment

However, semaglutide may also support blood sugar and appetite regulation for many patients