semaglutide and resting heart rate Can Weight Loss Injections Cause Problems? Safety Evidence Semaglutide Reverses Ectopic Lipid Accumulation,

There is still a lot of trial and error, Apovian told me

Even after treatment, this lower set point often persistsyou need fewer calories than someone who was never hypothyroid

Monitoring and Communication Keep a symptom diary noting bowel movement frequency, consistency, and any associated symptoms

Major cardiovascular outcome trials include: LEADER trial (liraglutide): Demonstrated a significant reduction in major adverse cardiovascular events (MACE) in patients with type 2 diabetes and high cardiovascular risk SUSTAIN-6 (semaglutide): Showed reduced cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke REWIND (dulaglutide): Confirmed cardiovascular benefits across a broad patient population SELECT trial (semaglutide): Showed reduced MACE in people with obesity without diabetes, though this evidence is not yet fully incorporated into UK labelling [17] These trials consistently found that the modest heart rate increases observed did not translate into adverse cardiovascular outcomes

Notify your provider about thyroid disease at intake, and continue regular TSH monitoring while starting treatment