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The sleep deprivation rat model of mania induces hyper-locomotion, increased sleep latency, and reduced hippocampal cell proliferation, with markers of pkc overactivity such as excess phosphorylated hippocampal and prefrontal synaptosomal-associated protein 25 (SNAP-25)

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To our knowledge, no preclinical or clinical investigations have been conducted to determine which of the multiple commercially available nutritional supplement products demonstrate superior results in aging women with estrogen-deficient skin

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