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In the FIGHT trial on patients hospitalized for HFrEF, Liraglutide did not show benefit on time to death, time to rehospitalization for heart failure, and time-averaged proportional change in N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels from baseline to 180 days [51]

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Movies were read into MATLAB using BioFormats (Open Microscope Environment), then vesicles exhibiting spike profiles and vesicles failing release with various levels of quinacrine intensity were manually selected, up to a total of 2030 vesicles per movie