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FcRn-ligand complexes are instead sorted into vesicles that traffic back to the plasma membrane and undergo exocytosis 42,43,44,45,46,49
31,32 In HIVAC, disruptions in autophagy machinery lead to accumulation of abnormal mitochondria independent of viral entry pathways, whereas Highly Active Antiretroviral Therapy (HAART) agents such as azidothymidine and abacavir further exacerbate autophagy defects
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However, published evidence should be interpreted according to the literature available for each individual peptide rather than assumed to demonstrate equivalent findings for the combined formulation
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