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The experts believe that the complementary rather than synergistic mechanisms of action make it unlikely that the well-known class effects of GLP1-RAs and SGLT2is will differ in combination

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Surgery confers multiple downstream benefits: Lower rates of obesity-related comorbidities (like hypertension, hyperlipidemia, sleep apnea) compared to GLP-1 therapy at follow-up JAMA Network Reduced health care utilization: fewer inpatient stays, outpatient visits, and ED visits per patient per month post-surgery compared to GLP-1 therapy

Improved taste: the liposomal encapsulation process masks the unpleasant taste of glutathione, making the supplement easier to administer