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If you find yourself needing more rest during this adjustment period, try to accommodate this need while maintaining your regular sleep routine

[40] collected blood samples (in EDTA-containing tubes), plasma was separated and stored at 80 C until further preparation for HPLC analysis

Educate patients and caregivers on how to recognize respiratory depression and emphasize the importance of calling 911 or getting emergency medical help right away in the event of a known or suspected overdose [see PRECAUTIONS, Information for Patients/Caregivers]

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