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The maintenance study FIGARO UC 303 (NCT03290781) enrolled 366 responders who continued their induction dose or switched to placebo for 52 weeks, demonstrating that both 25mg and 75mg doses significantly outperformed placebo with clinical remission rates of 53.5% and 40.2% respectively versus approximately 8-13% placebo, while inclusion criteria required patients aged 1866 years with moderate to severe disease and the completed studies showed favorable safety profiles with most common adverse events being UC worsening, arthralgia, and nasopharyngitis (51)

Some medicines, especially those known to cause liver toxicity, may interact with semaglutide or increase the risk of liver injury

However, studies have shown that GLP-1 and binge eating may be closely linked

Functionally, the intake-review-prescribe-ship sequence mirrors what most programs in this space use

Stanciu et al., 2019)