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The Fetal Immune System Early in development, the fetal immune system undergoes the process of self-education, principally in the fetal thymus: pre-lymphocytes that recognize self major histocompatibility complex (MHC) antigens are positively selected for, while those with high-affinity recognition of self-antigens are eliminated (Takahama, IUSCT Experimental Studies The notion of using the fetus as the recipient of stem cell transplantation traces back to the landmark finding that exposure to foreign antigens can result in immune tolerance

It converts two GSH molecules into oxidized glutathione (GSSG), and reduces lipid peroxide (PEs-AA/ADA-OOH) to the non-toxic corresponding lipid derived alcohol (PEs-AA/ADA-OH) to prevent the accumulation of harmful lipid peroxides (Maiorino et al