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These may include: Muscle cramps or weakness Increased heart rate Seizures in individuals with seizure disorders Worsening of hypothyroid symptoms Gastrointestinal discomfort in sensitive individuals If any of these symptoms occur, its important to discontinue use and seek medical advice immediately

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The recommended titration strategy involves increasing the dose by 2 units every 3 days until FPG levels are within the target range of 80130 mg/dL [59, 64]

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