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If nerve-related symptoms develop during semaglutide therapy, a systematic approach to evaluation and management is essential

In layperson terms, semaglutide makes you less hungry, so you eat less food, it slows your digestion, so the food you do eat sticks around longer and is more effectively used, and it stimulates the use of stored energy in the form of body fat to replace the nutrients you would have been eating, but aren't because you aren't hungry

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However, because GLP-1 itself is easily degraded in vivo, its short half-life limits its application as a diabetes treatment drug

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