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In NIH-3T3 mouse fibroblasts cells, pre-treatment with L2-Cmu led to an ~65% inhibition of IGF-1-mediated activation of IGF-1Rs and InsR/IGF-1R hybrid receptors (HybridRs) (Fig

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doi: 10.3389/fimmu.2020.00835 73 BianconiAArutaGRizzoFSalvatiLFZeppaPGarbossaDet al

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Similarly, UA stabilizes ascorbate in biological fluids by chelating iron to form a stable non-catalytic urateiron complex [38]