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It also helps to reduce appetite and curb hunger cravings

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The understanding that obesity is a polygenic disease is well-established, with leptin (LEP), leptin receptor (LEPR), melanocortin 4 receptor (MC4R), and proopiomelanocortin (POMC) being prominent contributors

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What clinical trials show Large-scale clinical trials have measured average weight loss across thousands of participants: Wegovy (semaglutide 2.4 mg) : Participants in the STEP 1 trial lost an average of 14.9% of their body weight over 68 weeks