Muscle is important for keeping your metabolism humming, helping your body use insulin better, and just generally keeping you strong and mobile long-term
Mayhew AJ, de Souza RJ, Meyre D, Anand SS, Mente A
As a result, IGF-1 LR3 remains active in the bloodstream for a longer period, enhancing its efficacy in promoting growth and anabolic processes
This occurs because weight loss lowers estrogen levels
In this global registration trial, where 84.0% of participants had a baseline BMI of 35 kg/m, each dose of retatrutide (9 mg and 12 mg) met all primary and key secondary endpoints, delivering significant weight loss and improvements in pain and physical function at 68 weeks using both the efficacy and treatment-regimen estimands