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Seek urgent medical attention (via NHS 111 or 999 if severe) if you experience any of the following whilst taking Mounjaro after gastric bypass: Severe or persistent vomiting that prevents adequate fluid or nutrition intake Signs of dehydration , including dark urine, dizziness, reduced urination, or extreme thirst Symptoms of hypoglycaemia , such as trembling, sweating, confusion, rapid heartbeat, or loss of consciousness Severe abdominal pain , particularly if accompanied by fever or vomiting, which could indicate pancreatitis or gallbladder disease (stop taking tirzepatide immediately) Sustained rapid or unintentional weight loss with inability to meet nutritional or hydration needs Signs of nutritional deficiency , including extreme fatigue, weakness, numbness or tingling in extremities, or cognitive changes Routine consultations with your healthcare team should occur if you notice reduced effectiveness of the medication, intolerable side effects affecting quality of life, difficulty maintaining adequate protein or fluid intake, or any concerns about your nutritional status

If you have baseline GERD, discuss your reflux history with your healthcare provider before starting any GLP-1 medication

Karunnanithy A, et al

GLP-1 medications such as semaglutide and tirzepatide work by slowing gastric emptying and enhancing satiety hormones, causing most patients to naturally eat significantly less without feeling deprived

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