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Nutritional factors in the aetiology of multiple sclerosis: a case-control study in Montreal, Canada

For immune support during illness, high-dose recovery, or skin health, IV vitamin C is dramatically more effective

However, a very wide-range of values for cytosolic NADPH/NADP + has been reported in the literature 36,56,57,58

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Need for in vivo documentations in humans The above mentioned studies are mainly based on in vitro and preclinical data, while the field would largely benefit from a more solid documentation of the capacity of riboflavin-producing organisms to increase riboflavin in vivo in humans by for example metagenomic/proteomic/metabolomic studies of the gut and vaginal microbiomes