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This drug should not be used in patients with type 1 diabetes mellitus Use: As an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus Renal Dose Adjustments Renal dysfunction: No adjustment recommended

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Clin Endocrinol (Oxf) (2003) 59:3217

More recently, a meta-analysis that included 48 randomized-controlled trials was performed to compare different strategies of CIN prevention versus hydration in patients with chronic kidney disease undergoing coronary angiography [182]

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