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Mounjaros NCPE reimbursement review, expected in 2026, may change the picture, it is considered a stronger candidate than Wegovy, given greater efficacy and a different active ingredient to Ozempic

[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Gojkovic S., Krezic I., Vrdoljak B., Malekinusic D., Barisic I., Petrovic A., Pavlov K.H., Kolovrat M., Duzel A., Knezevic M., et al

Ligand specificity GLP-2 and GLP-1 share high sequence similarity (69.7%) and have almost identical residues in two regions: the N-terminus (first six residues in GLP-2) that penetrates into the TMD core, and the C-terminus (residues 1833) that is recognized by the ECD and ECL1 of the receptor

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