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We discuss tumor cell populations and their evolution, interactions between tumor cells and the microenvironment, new prognostic markers, and clinically important targets

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Cell Death Dis 15 , 481 (2024)

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With careful dose titration and timing to align with meals, the risk of insulin oversupply and hypoglycaemia can be minimised, and several glucokinase activators with variable effects on beta cells vs liver have improved glycaemic control in clinical studies [21]